Peptide Active Data Details
Basic Peptide Information
DICL ID
DICL_Pep_02818
Ion Channel
Sodium channel type 4 subunit alpha
Peptide Function
Inhibitor
Gene Name
Scn4a
Activity Data (nM)
IC50
48 nM
Ki
Not available
EC50
Not available
Kd
Not available
Biologically Active
Not specified
Sequence Information
Peptide Sequence
CCNCSSKWCRDHSRCC
Peptide UniProt Accession
UniParc
UPI0000603521
Peptide Synonyms/Alias
[mu-Conotoxin K IIIA; UNII-390H5GUO40; CHEMBL2402969; 390H5GUO40; 884469-67-4; Ccncsskwcrdhsrcc-NH2 cyclic (1->9);(2->15);(4->16); L-Cysteinamide; L-cysteinyl-L-cysteinyl-L-asparaginyl-L-cysteinyl-L-seryl-L-seryl-L-lysyl-L-tryptophyl-L-cysteinyl-L-arginyl-L-alpha-aspartyl-L-histidyl-L-seryl-L-arginyl-L-cysteinyl-; cyclic (1->9);(2->15);(4->16)-tris(disulfide); mu-Conotoxin KIIIA; BDBM50492340; DA-68915]
Peptide Species
Conus kinoshitai
Peptide Name
Mu-conotoxin KIIIB
CAS Number
884469-67-4
Experimental Conditions
pH
pH 7.3
Holding Potential (mV)
−80 mV
Temperature
Not mention
Test Method
Patch-clamping
Test Species
HEK293 cell (Homo sapiens embryonic kidney 293 cell)
Binding Information
Binding Site
Extracellular domain
Binding Site Residue
residues K7, W8, R10, D11, and R14
Ion Channel Information
Gene Abbreviation (ABB)
VGSCs
Ion Channel UniProt Accession
Source Organism
Rattus norvegicus (Rat)
References & Disease Information
Disease
Not specified
PubChem CID
URL
Not available
PMID
Patent
Not available